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Two new studies offer hope for Canadians who have suffered a heart attack
(NC)-Cardiovascular disease remains a leading cause of death in Canada; sadly, almost every Canadian knows or has met someone who has experienced a heart attack.
 
Many of us also know someone who did not survive one.
What many Canadians don't know is that in many cases, a heart attack is the result of a condition called atherothrombosis - a blood clot that forms in a blood vessel, disrupting the flow of blood - and can be prevented. If an artery leading to a heart is fully or almost completely blocked, a heart attack occurs.
 
What is Atherothrombosis?
 
Atherothrombosis is a progressive and lifelong disease that affects the body's network of blood vessels. Put simply, blood clots form on fatty deposits in the inside wall of an artery and the flow of blood is disrupted. If there is a disruption of the blood flow in the affected artery, oxygen-rich blood is unable to reach the tissues on the other side of the clot and the oxygen-starved cells begin to die.
 
Atherothrombosis can lead to serious and potentially life-threatening conditions including stroke, heart attack and peripheral arterial disease (PAD), or blockages in the legs.
Patients admitted to hospital with a heart attack will in many cases require surgery or another medical procedure (angioplasty) to open their arteries. However, the arteries may re-close and a new blockage puts a patient at risk of another heart attack.
 
The good news is that results of two recent studies suggest that an antiplatelet treatment saves lives and prevents a second heart attack in these patients: the CLARITY and COMMIT studies demonstrated that when combined with the standard therapy, the antiplatelet drug Plavix helps patients maintain open arteries and live longer, following serious heart attacks.
 
In fact, the CLARITY study, which included 3,000 Canadians, demonstrated that patients who took Plavix had a 36 per cent reduced chance of having a re-closed artery or a second heart attack, or dying after one week of hospitalization compared to another group that only took the standard medications. Furthermore, the results of the COMMIT study showed that Plavix reduced death in patients with acute heart attack by seven per cent and the relative risk of the combination of recurrent heart attack, stroke or death by nine per cent.
 
What Can You Do?
 
Lifestyle modifications - such as quitting smoking or improving your diet - are the first steps in managing atherothrombosis and preventing or reducing the risk of a first or recurrent atherothrombotic event (heart attack or stroke). Medical treatment is also needed in many cases, especially in people who have already suffered a heart attack or stroke and thus are at an increased risk of having another life-threatening event.
 
The key goal for treatments related to atherothrombosis is the prevention of further blood clots. Doctors often prescribe patients antiplatelets, such as Plavix, to decrease the possibility of the body forming another blood clot. Antiplatelet therapies prevent platelets from sticking together in the bloodstream; this helps blood flow more easily, reducing the risk of a future heart attack or stroke.
 
Courtesy of News Canada
 

 
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